Artvigil 150 mg is routinely used to increase wakefulness, although its long-term safety has not been proved. Many people tolerate it well, but long-term use may raise the risk of side effects such headaches, sleeplessness, anxiety, or high blood pressure. Because it alters neurotransmitters, prolonged use without medical supervision may bring extra concerns, such as dependence or decreased effectiveness over time.

Regular check-ins with a healthcare physician are essential for monitoring sleep habits, cardiovascular health, and overall tolerance. While Artvigil is effective, long-term use should always be monitored by a doctor to ensure safe and proper treatment.